Antibiotics in Pregnancy
Antibiotics which are safe for pregnancy penicillin, erythromycin
clindamycin cephalosporins.
Prophylactic Antibiotics
Ampocillin, amoxicillin, cefazolin, and erythromycin/sulbactam
are the safest drug to treat the preterm premature rupture of membrane,
prevention of bacterial endocarditis and during cesarean section, urinary tract
infection, chorio-amnionitis and group B streptococci.
Antibiotics to be avoided
Following drugs to be avoided:
Ø
Amino glycosides = eight cranial nerve damage
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Erythromycin estolate = hepatotoxic to mother
Ø
Fluoroquinolones = potentially mutagenic,
cartilage damage, arthopathy, teratogenicity
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Ribavarin = possibly fetotoxic
Ø
Tetracyclines = staining of deciduous teeth.
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